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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSHZ3
All Species:
31.82
Human Site:
Y239
Identified Species:
77.78
UniProt:
Q63HK5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HK5
NP_065907.2
1081
118566
Y239
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Chimpanzee
Pan troglodytes
XP_512561
1070
117230
Y228
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Rhesus Macaque
Macaca mulatta
XP_001103809
1081
118554
Y239
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Dog
Lupus familis
XP_541721
1137
124213
Y295
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGV9
1081
118608
Y239
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Rat
Rattus norvegicus
NP_001100976
1038
113807
R216
R
W
S
K
P
R
K
R
S
L
L
E
M
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508239
1194
130249
Y352
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Chicken
Gallus gallus
XP_414125
1073
117771
Y233
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Frog
Xenopus laevis
NP_001090569
1004
110567
R182
T
D
N
K
N
P
K
R
W
S
K
P
R
K
R
Zebra Danio
Brachydanio rerio
XP_694172
1191
130444
Y312
H
M
N
E
T
G
H
Y
R
D
D
N
H
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.4
89.1
N.A.
95.1
91.8
N.A.
83.5
90.9
81.4
68.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
99.6
91.8
N.A.
97.6
93.5
N.A.
86.9
95
86.8
78.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
6.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
100
20
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
80
80
0
0
0
0
% D
% Glu:
0
0
0
80
0
0
0
0
0
0
0
10
0
90
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
10
% G
% His:
80
0
0
0
0
0
80
0
0
0
0
0
80
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
20
0
0
20
0
0
0
10
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% L
% Met:
0
80
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
90
0
10
0
0
0
0
0
0
80
0
0
0
% N
% Pro:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
20
80
0
0
0
10
0
10
% R
% Ser:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% S
% Thr:
10
0
0
0
80
0
0
0
0
0
0
0
0
0
80
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _